There’s something incredibly comforting about a slow-cooked meal that fills your home with irresistible aromas. The Mississippi Pot Roast Slow Cooker Recipe is a perfect example of this—it’s tender, flavorful, and so easy to prepare. Just toss a few ingredients into the slow cooker, and let it do all the work. This dish is a family favorite that will quickly become a staple in your meal rotation.
Why I Love This Recipe

One of the reasons I adore this Mississippi Pot Roast recipe is its simplicity. With just a handful of ingredients, you can create a hearty and satisfying meal. The blend of spices, pepperoncini, and beef broth infuses the roast with incredible flavor, while the slow cooking process ensures the meat is melt-in-your-mouth tender. It’s a one-pot wonder that requires minimal effort, making it perfect for busy weeknights or lazy weekends. Plus, the leftovers are just as delicious, making it a perfect dish for meal prep!
Shopping List
- 3-5 pounds boneless chuck roast, trimmed of excess fat
- 1 teaspoon onion powder
- 1 teaspoon garlic powder
- 1/2 teaspoon pepper
- 1 tablespoon vegetable oil
- 5 garlic cloves, peeled
- 2 cups low sodium beef broth
- 1/3 cup pepperoncini juice (from jar of pepperoncini)
- 2 tablespoons reduced sodium soy sauce
- 3 tablespoons dried minced onions
- 1 tablespoon granulated beef bouillon
- 2 teaspoons dried parsley
- 1 teaspoon dried chives
- 1 teaspoon dried dill
- 1/2 teaspoon dried oregano
- 1 bay leaf
- 8 whole pepperoncini
- Carrots (cut into thirds) – optional
- Baby red potatoes – optional
- 1/4 cup butter
- 1/4 cup flour
- 2 cups beef broth from slow cooker
Cook’s Kit
- Slow Cooker – A must-have for this recipe, ensuring even cooking.
- Meat Thermometer – To check for doneness, ensuring your roast is cooked perfectly.
- Cutting Board – For trimming the roast and preparing vegetables.
- Chef’s Knife – Essential for chopping and cutting ingredients.
- Serving Spoon – To serve up the delicious pot roast and gravy.
Mississippi Pot Roast Slow Cooker Recipe Made Stepwise

Step 1: Prep the Chuck Roast
Begin by trimming any excess fat from your boneless chuck roast. This helps reduce greasiness in the final dish.
Step 2: Season the Meat
In a small bowl, mix together the onion powder, garlic powder, and pepper. Rub this seasoning blend all over the roast, ensuring it is well coated.
Step 3: Sear the Roast
In a large skillet, heat the vegetable oil over medium-high heat. Once hot, add the seasoned roast and sear it for about 4-5 minutes on each side until browned. This step adds depth of flavor to your pot roast.
Step 4: Prepare the Slow Cooker
Transfer the seared roast to the slow cooker. Add the peeled garlic cloves, beef broth, pepperoncini juice, soy sauce, dried minced onions, beef bouillon, dried parsley, chives, dill, oregano, bay leaf, and whole pepperoncini.
Step 5: Optional Vegetables
If you’re adding carrots and baby red potatoes, place them around the roast in the slow cooker. They will absorb the delicious juices and enhance the overall flavor.
Step 6: Cook
Cover the slow cooker and cook on low for 8-10 hours or high for 4-6 hours, until the roast is fork-tender and flavorful.
Step 7: Make the Gravy
Once the roast is done, remove it from the slow cooker and let it rest. In a saucepan, melt the butter over medium heat. Whisk in the flour to create a roux, cooking for 1-2 minutes until golden. Gradually add in 2 cups of the beef broth from the slow cooker, whisking continuously until thickened.
Step 8: Serve
Slice or shred the roast and serve it with the rich gravy over the top. Enjoy it with the carrots and potatoes for a complete meal!
Ingredient Flex Options

- Chuck Roast: You can substitute with a rump roast or brisket if desired.
- Vegetable Oil: Olive oil or avocado oil can be used as alternatives.
- Low Sodium Beef Broth: Homemade beef broth can be used for a richer flavor.
- Pepperoncini: If unavailable, banana peppers can work as a substitute.
- Vegetables: Feel free to add other vegetables like onions or celery for extra flavor.
Mistakes Even Pros Make
- Skipping the searing step: Searing the meat adds vital flavor that enhances the final dish.
- Overcooking: Make sure to monitor the cooking time; overcooked meat can become dry.
- Not using enough liquid: Ensure there’s enough broth to keep the meat moist while cooking.
- Forgetting to trim the fat: Leaving too much fat can make the dish greasy instead of rich and flavorful.
Storage & Reheat Guide
Leftover Mississippi Pot Roast can be stored in an airtight container in the refrigerator for up to 4 days. To reheat, place the roast and gravy in a saucepan over low heat, stirring occasionally until warmed through. You can also use the microwave; just cover it to prevent splatters and heat in intervals, checking frequently.
If you want to store the pot roast for longer, freeze it in a freezer-safe container for up to 3 months. Thaw in the refrigerator overnight before reheating for the best results.
Helpful Q&A
Can I use a different cut of meat?
Yes! While chuck roast is preferred for its tenderness and flavor, you can use other cuts like brisket or rump roast, but cooking times may vary slightly.
Can I cook this on the stovetop instead of a slow cooker?
Absolutely! You can adapt this recipe for the stovetop by using a Dutch oven. Sear the roast, add the ingredients, and simmer on low for about 2-3 hours, or until tender.
What can I serve with Mississippi Pot Roast?
This dish pairs wonderfully with mashed potatoes, rice, or crusty bread to soak up the delicious gravy. A simple green salad is also a great side for balance.
Can I make this recipe ahead of time?
Yes! You can prepare the ingredients the night before and store them in the refrigerator. Just pop them into the slow cooker in the morning, and you’ll have a delicious meal ready by dinner time!
Next Up in Your Queue
Next Steps
Now that you have the Mississippi Pot Roast Slow Cooker Recipe, it’s time to gather your ingredients and get cooking! This dish is not only a crowd-pleaser but also a fantastic way to enjoy a hearty meal without spending all day in the kitchen. Don’t forget to share your culinary creations with family and friends, and enjoy the warm, comforting flavors that this recipe brings to your table. Happy cooking!

Mississippi Pot Roast Slow Cooker Recipe
Ingredients
For the Roast:
- 3-5 pounds boneless chuck roast trimmed of excess fat
- 1 teaspoon onion powder
- 1 teaspoon garlic powder
- 1/2 teaspoon pepper
- 1 tablespoon vegetable oil
- 5 cloves garlic peeled
- 2 cups low sodium beef broth
- 1/3 cup pepperoncini juice (from jar of pepperoncini)
- 2 tablespoons reduced sodium soy sauce
- 3 tablespoons dried minced onions
- 1 tablespoon granulated beef bouillon
- 2 teaspoons dried parsley
- 1 teaspoon dried chives
- 1 teaspoon dried dill
- 1/2 teaspoon dried oregano
- 8 whole pepperoncini
- Carrots (cut into thirds) - optional
- Baby red potatoes - optional
- 1/4 cup butter
- 1/4 cup flour
- 2 cups beef broth (from slow cooker)
Instructions
Instructions:
- Begin by trimming any excess fat from your boneless chuck roast. This helps reduce greasiness in the final dish.
- In a small bowl, mix together the onion powder, garlic powder, and pepper. Rub this seasoning blend all over the roast, ensuring it is well coated.
- In a large skillet, heat the vegetable oil over medium-high heat. Once hot, add the seasoned roast and sear it for about 4-5 minutes on each side until browned.
- Transfer the seared roast to the slow cooker. Add the peeled garlic cloves, beef broth, pepperoncini juice, soy sauce, dried minced onions, beef bouillon, dried parsley, chives, dill, oregano, bay leaf, and whole pepperoncini.
- If you’re adding carrots and baby red potatoes, place them around the roast in the slow cooker.
- Cover the slow cooker and cook on low for 8-10 hours or high for 4-6 hours, until the roast is fork-tender and flavorful.
- Once the roast is done, remove it from the slow cooker and let it rest. In a saucepan, melt the butter over medium heat. Whisk in the flour to create a roux, cooking for 1-2 minutes until golden.
- Gradually add in 2 cups of the beef broth from the slow cooker, whisking continuously until thickened.
- Slice or shred the roast and serve it with the rich gravy over the top. Enjoy it with the carrots and potatoes for a complete meal!
Equipment
- Slow Cooker
- Large Skillet
- Meat thermometer
- Cutting Board
- Chef’s knife
- Serving spoon
Notes
- Leftover Mississippi Pot Roast can be stored in an airtight container in the refrigerator for up to 4 days.
- To reheat, place the roast and gravy in a saucepan over low heat, stirring occasionally until warmed through.
- For longer storage, freeze it in a freezer-safe container for up to 3 months.
